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ERBB4 confers metastatic capacity in Ewing sarcoma
Metastatic spread is the single-most powerful predictor of poor outcome in Ewing sarcoma (ES). Therefore targeting pathways that drive metastasis has tremendous potential to reduce the burden of disease in ES. We previously showed that activation of the ERBB4 tyrosine kinase suppresses anoikis, or d...
Autores principales: | Mendoza-Naranjo, Ariadna, El-Naggar, Amal, Wai, Daniel H, Mistry, Priti, Lazic, Nikola, Ayala, Fernanda Rocha Rojas, da Cunha, Isabela Werneck, Rodriguez-Viciana, Pablo, Cheng, Hongwei, Tavares Guerreiro Fregnani, Jose H, Reynolds, Patrick, Arceci, Robert J, Nicholson, Andrew, Triche, Timothy J, Soares, Fernando A, Flanagan, Adrienne M, Wang, Yuzhuo Z, Strauss, Sandra J, Sorensen, Poul H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721475/ https://www.ncbi.nlm.nih.gov/pubmed/23681745 http://dx.doi.org/10.1002/emmm.201202343 |
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