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Caudo-rostral brain spreading of α-synuclein through vagal connections

α-Synuclein accumulation and pathology in Parkinson's disease typically display a caudo-rostral pattern of progression, involving neuronal nuclei in the medulla oblongata at the earliest stages. In this study, selective expression and accumulation of human α-synuclein within medullary neurons w...

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Detalles Bibliográficos
Autores principales: Ulusoy, Ayse, Rusconi, Raffaella, Pérez-Revuelta, Blanca I, Musgrove, Ruth E, Helwig, Michael, Winzen-Reichert, Bettina, Monte, Donato A Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721477/
https://www.ncbi.nlm.nih.gov/pubmed/23703938
http://dx.doi.org/10.1002/emmm.201302475