Pharmacology of Rasagiline, a New MAO-B Inhibitor Drug for the Treatment of Parkinson’s Disease with Neuroprotective Potential

Rasagiline (Azilect) is a highly selective and potent propargylamine inhibitor of monoamine oxidase (MAO) type B. Like other similar propargylamine inhibitors, rasagiline binds covalently to the N5 nitrogen of the flavin residue of MAO, resulting in irreversible inactivation of the enzyme. Therapeut...

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Detalles Bibliográficos
Autor principal: Finberg, John P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2010
Materias:
Discoveries from the Bench to the Bedside
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721659/
https://www.ncbi.nlm.nih.gov/pubmed/23908775
http://dx.doi.org/10.5041/RMMJ.10003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721659/
https://www.ncbi.nlm.nih.gov/pubmed/23908775
http://dx.doi.org/10.5041/RMMJ.10003

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