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Discovery of bisulfite-mediated cytosine conversion to uracil, the key reaction for DNA methylation analysis — A personal account
Methylation at position 5 of cytosine in DNA is being intensively studied in many areas of biological sciences, as the methylation is intimately associated with the control of gene functions. The principal analytical method for determining the sites of 5-methylcytosine in genome at the sequence leve...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Japan Academy
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722019/ https://www.ncbi.nlm.nih.gov/pubmed/18941305 http://dx.doi.org/10.2183/pjab/84.321 |