Cargando…

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype

BACKGROUND: The N-methyl-D-aspartate receptors are key mediators of excitatory transmission and are implicated in many forms of synaptic plasticity. These receptors are heterotetrameres consisting of two obligatory NR1 and two regulatory subunits, usually NR2A or NR2B. The NR2B subunits are abundant...

Descripción completa

Detalles Bibliográficos
Autores principales: Maier, Wladislaw, Bednorz, Mariola, Meister, Sabrina, Roebroek, Anton, Weggen, Sascha, Schmitt, Ulrich, Pietrzik, Claus U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722104/
https://www.ncbi.nlm.nih.gov/pubmed/23866919
http://dx.doi.org/10.1186/1750-1326-8-25