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Endoplasmic Reticulum Aminopeptidase-1 Functions Regulate Key Aspects of the Innate Immune Response

Endoplasmic reticulum aminopeptidase-1 (ERAP1) is a multifunctional, ubiquitously expressed enzyme whose peptide-trimming role during antigen processing for presentation by MHC I molecules is well established, however, a role for ERAP1 in modulating global innate immune responses has not been descri...

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Detalles Bibliográficos
Autores principales: Aldhamen, Yasser A., Seregin, Sergey S., Rastall, David P. W., Aylsworth, Charles F., Pepelyayeva, Yuliya, Busuito, Christopher J., Godbehere-Roosa, Sarah, Kim, Sungjin, Amalfitano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722114/
https://www.ncbi.nlm.nih.gov/pubmed/23894499
http://dx.doi.org/10.1371/journal.pone.0069539