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Endoplasmic Reticulum Aminopeptidase-1 Functions Regulate Key Aspects of the Innate Immune Response
Endoplasmic reticulum aminopeptidase-1 (ERAP1) is a multifunctional, ubiquitously expressed enzyme whose peptide-trimming role during antigen processing for presentation by MHC I molecules is well established, however, a role for ERAP1 in modulating global innate immune responses has not been descri...
Autores principales: | Aldhamen, Yasser A., Seregin, Sergey S., Rastall, David P. W., Aylsworth, Charles F., Pepelyayeva, Yuliya, Busuito, Christopher J., Godbehere-Roosa, Sarah, Kim, Sungjin, Amalfitano, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722114/ https://www.ncbi.nlm.nih.gov/pubmed/23894499 http://dx.doi.org/10.1371/journal.pone.0069539 |
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