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Nonlinear Mixed-Effects Modelling of In Vitro Drug Susceptibility and Molecular Correlates of Multidrug Resistant Plasmodium falciparum

The analysis of in vitro anti-malarial drug susceptibility testing is vulnerable to the effects of different statistical approaches and selection biases. These confounding factors were assessed with respect to pfmdr1 gene mutation and amplification in 490 clinical isolates. Two statistical approache...

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Detalles Bibliográficos
Autores principales: Simpson, Julie A., Jamsen, Kris M., Anderson, Tim J. C., Zaloumis, Sophie, Nair, Shalini, Woodrow, Charles, White, Nicholas J., Nosten, Francois, Price, Ric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722116/
https://www.ncbi.nlm.nih.gov/pubmed/23894496
http://dx.doi.org/10.1371/journal.pone.0069505