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Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites

Sterile immunity against live Plasmodium infection can be achieved by immunization with radiation attenuated sporozoites. This protection is known to be mediated in part by antigen-specific memory CD8(+) T cells, presumably those residing in the liver. We characterized and compared the transcription...

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Detalles Bibliográficos
Autores principales: Tse, Sze-Wah, Cockburn, Ian A., Zhang, Hao, Scott, Alan L., Zavala, Fidel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722257/
https://www.ncbi.nlm.nih.gov/pubmed/23594961
http://dx.doi.org/10.1038/gene.2013.20