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An Integrated Tool to Study MHC Region: Accurate SNV Detection and HLA Genes Typing in Human MHC Region Using Targeted High-Throughput Sequencing

The major histocompatibility complex (MHC) is one of the most variable and gene-dense regions of the human genome. Most studies of the MHC, and associated regions, focus on minor variants and HLA typing, many of which have been demonstrated to be associated with human disease susceptibility and meta...

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Detalles Bibliográficos
Autores principales: Cao, Hongzhi, Wu, Jinghua, Wang, Yu, Jiang, Hui, Zhang, Tao, Liu, Xiao, Xu, Yinyin, Liang, Dequan, Gao, Peng, Sun, Yepeng, Gifford, Benjamin, D’Ascenzo, Mark, Liu, Xiaomin, Tellier, Laurent C. A. M., Yang, Fang, Tong, Xin, Chen, Dan, Zheng, Jing, Li, Weiyang, Richmond, Todd, Xu, Xun, Wang, Jun, Li, Yingrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722289/
https://www.ncbi.nlm.nih.gov/pubmed/23894464
http://dx.doi.org/10.1371/journal.pone.0069388