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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye disease that usually does not lead to complete blindness, but can result in severe loss of central vision. Risk factors for AMD include age, genetics, diet, smoking, oxidative stress and many cardiovascular-associa...

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Detalles Bibliográficos
Autores principales: Kaarniranta, Kai, Sinha, Debasish, Blasiak, Janusz, Kauppinen, Anu, Veréb, Zoltán, Salminen, Antero, Boulton, Michael E., Petrovski, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722332/
https://www.ncbi.nlm.nih.gov/pubmed/23590900
http://dx.doi.org/10.4161/auto.24546