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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye disease that usually does not lead to complete blindness, but can result in severe loss of central vision. Risk factors for AMD include age, genetics, diet, smoking, oxidative stress and many cardiovascular-associa...
Autores principales: | Kaarniranta, Kai, Sinha, Debasish, Blasiak, Janusz, Kauppinen, Anu, Veréb, Zoltán, Salminen, Antero, Boulton, Michael E., Petrovski, Goran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722332/ https://www.ncbi.nlm.nih.gov/pubmed/23590900 http://dx.doi.org/10.4161/auto.24546 |
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