Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

Failure to engage apoptosis appears to be a leading mechanism of resistance to traditional platinum drugs in patients with ovarian cancer. Therefore, an alternative strategy to induce cell death is needed for the chemotherapy of this apoptosis-resistant cancer. Here we report that autophagic cell de...

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Detalles Bibliográficos
Autores principales: Guo, Wen-Jie, Zhang, Yang-Miao, Zhang, Li, Huang, Bin, Tao, Fei-Fei, Chen, Wei, Guo, Zi-Jian, Xu, Qiang, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722334/
https://www.ncbi.nlm.nih.gov/pubmed/23580233
http://dx.doi.org/10.4161/auto.24407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722334/
https://www.ncbi.nlm.nih.gov/pubmed/23580233
http://dx.doi.org/10.4161/auto.24407

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