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Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease

Amyloid-β (Aβ) plaque deposition plays a central role in the pathogenesis of Alzheimer’s disease (AD). Post-mortem analysis of plaque development in mouse models of AD revealed that plaques are initially small, but then increase in size and become more numerous with age. There is evidence that plaqu...

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Detalles Bibliográficos
Autores principales: McCarter, Joanna F., Liebscher, Sabine, Bachhuber, Teresa, Abou-Ajram, Claudia, Hübener, Mark, Hyman, Bradley T., Haass, Christian, Meyer-Luehmann, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722456/
https://www.ncbi.nlm.nih.gov/pubmed/23775142
http://dx.doi.org/10.1007/s00401-013-1137-2