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Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease
Amyloid-β (Aβ) plaque deposition plays a central role in the pathogenesis of Alzheimer’s disease (AD). Post-mortem analysis of plaque development in mouse models of AD revealed that plaques are initially small, but then increase in size and become more numerous with age. There is evidence that plaqu...
Autores principales: | McCarter, Joanna F., Liebscher, Sabine, Bachhuber, Teresa, Abou-Ajram, Claudia, Hübener, Mark, Hyman, Bradley T., Haass, Christian, Meyer-Luehmann, Melanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722456/ https://www.ncbi.nlm.nih.gov/pubmed/23775142 http://dx.doi.org/10.1007/s00401-013-1137-2 |
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