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A Pilot Study of Fluorodeoxyglucose Positron Emission Tomography Findings in Patients with Phenylketonuria before and during Sapropterin Supplementation

BACKGROUND AND PURPOSE: PET scanning with fluorodeoxyglucose (FDG-PET) is a non-invasive method that measures regional glucose metabolic rate. Phenylalanine (Phe) and its metabolites appear to impair several aspects of brain energy metabolism. 1) To evaluate brain glucose metabolism with FDG-PET ima...

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Detalles Bibliográficos
Autores principales: Ficicioglu, Can, Dubroff, Jacob G, Thomas, Nina, Gallagher, Paul R, Burfield, Jessica, Hussa, Christie, Randall, Rebecca, Zhuang, Hongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurological Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722466/
https://www.ncbi.nlm.nih.gov/pubmed/23894238
http://dx.doi.org/10.3988/jcn.2013.9.3.151