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Amyloid-β induces synaptic dysfunction through G protein-gated inwardly rectifying potassium channels in the fimbria-CA3 hippocampal synapse

Last evidences suggest that, in Alzheimer's disease (AD) early stage, Amyloid-β (Aβ) peptide induces an imbalance between excitatory and inhibitory neurotransmission systems resulting in the functional impairment of neural networks. Such alterations are particularly important in the septohippoc...

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Detalles Bibliográficos
Autores principales: Nava-Mesa, Mauricio O., Jiménez-Díaz, Lydia, Yajeya, Javier, Navarro-Lopez, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722514/
https://www.ncbi.nlm.nih.gov/pubmed/23898239
http://dx.doi.org/10.3389/fncel.2013.00117