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Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers

Recent clinical trials of small interfering RNAs (siRNAs) highlight the need for robust delivery technologies that will facilitate the successful application of these therapeutics to humans. Arguably, cell targeting by conjugation to cell-specific ligands provides a viable solution to this problem....

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Detalles Bibliográficos
Autores principales: Hernandez, Luiza I., Flenker, Katie S., Hernandez, Frank J., Klingelhutz, Aloysius J., II, James O. McNamara, Giangrande, Paloma H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722562/
https://www.ncbi.nlm.nih.gov/pubmed/23894227
http://dx.doi.org/10.3390/ph6030295