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Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals

Toll-like receptors (TLRs) are widely expressed and play an essential role in the activation of innate immune cells. However, certain TLRs are also expressed on T cells, and TLR ligands can directly modulate T cell functions. Here, we discuss findings indicating that T cells directly respond to Heat...

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Detalles Bibliográficos
Autores principales: Zanin-Zhorov, Alexandra, Cohen, Irun R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722573/
https://www.ncbi.nlm.nih.gov/pubmed/23898332
http://dx.doi.org/10.3389/fimmu.2013.00211