Can RNAi-mediated hsp90α knockdown in combination with 17-AAG be a therapy for glioma?()

Heat shock protein 90 promotes tumor progression and survival and has emerged as a vital therapeutic target. Previously we reported that the combinatorial treatment of 17AAG/sihsp90α significantly downregulated Hsp90α mRNA and protein levels in Glioblastoma Multiforme (GBM). Here we investigated the...

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Detalles Bibliográficos
Autores principales: Mehta, Adi, Shervington, Amal, Howl, John, Jones, Sarah, Shervington, Leroy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722647/
https://www.ncbi.nlm.nih.gov/pubmed/23905009
http://dx.doi.org/10.1016/j.fob.2013.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722647/
https://www.ncbi.nlm.nih.gov/pubmed/23905009
http://dx.doi.org/10.1016/j.fob.2013.06.002

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