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Can RNAi-mediated hsp90α knockdown in combination with 17-AAG be a therapy for glioma?()
Heat shock protein 90 promotes tumor progression and survival and has emerged as a vital therapeutic target. Previously we reported that the combinatorial treatment of 17AAG/sihsp90α significantly downregulated Hsp90α mRNA and protein levels in Glioblastoma Multiforme (GBM). Here we investigated the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722647/ https://www.ncbi.nlm.nih.gov/pubmed/23905009 http://dx.doi.org/10.1016/j.fob.2013.06.002 |