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Interleukin-33 Drives Activation of Alveolar Macrophages and Airway Inflammation in a Mouse Model of Acute Exacerbation of Chronic Asthma

We investigated the role of interleukin-33 (IL-33) in airway inflammation in an experimental model of an acute exacerbation of chronic asthma, which reproduces many of the features of the human disease. Systemically sensitized female BALB/c mice were challenged with a low mass concentration of aeros...

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Detalles Bibliográficos
Autores principales: Bunting, Melissa M., Shadie, Alexander M., Flesher, Rylie P., Nikiforova, Valentina, Garthwaite, Linda, Tedla, Nicodemus, Herbert, Cristan, Kumar, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722780/
https://www.ncbi.nlm.nih.gov/pubmed/23936781
http://dx.doi.org/10.1155/2013/250938