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CTLA-4 Expression and Polymorphisms in Lung Tissue of Patients with Diagnosed Non-Small-Cell Lung Cancer

Cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) is a potent immunoregulatory molecule that downregulates T-cell activation and thus influences the antitumor immune response. CTLA-4 polymorphisms are associated with various cancers, and CTLA-4 mRNA/protein increased expression is found in severa...

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Detalles Bibliográficos
Autores principales: Antczak, Adam, Pastuszak-Lewandoska, Dorota, Górski, Paweł, Domańska, Daria, Migdalska-Sęk, Monika, Czarnecka, Karolina, Nawrot, Ewa, Kordiak, Jacek, Brzeziańska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722891/
https://www.ncbi.nlm.nih.gov/pubmed/23936819
http://dx.doi.org/10.1155/2013/576486