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Involvement of high mobility group box 1 and the therapeutic effect of recombinant thrombomodulin in a mouse model of severe acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is accompanied by severe lung inflammation induced by various diseases. Despite the severity of the symptoms, therapeutic strategies have been ineffective. High mobility group box 1 (HMGB1), which was identified originally as a DNA binding protein, has been...

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Detalles Bibliográficos
Autores principales: Kudo, D, Toyama, M, Aoyagi, T, Akahori, Y, Yamamoto, H, Ishii, K, Kanno, E, Maruyama, R, Kaku, M, Kushimoto, S, Kawakami, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722928/
https://www.ncbi.nlm.nih.gov/pubmed/23607598
http://dx.doi.org/10.1111/cei.12106