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Synthesis and Biological Evaluation of O-[3-(18)F-fluoropropyl]-α-methyl Tyrosine in Mesothelioma-Bearing Rodents

Radiolabeled tyrosine analogs enter cancer cells via upregulated amino acid transporter system and have been shown to be superior to (18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) in differential diagnosis in cancers. In this study, we synthesized O-[3-(19)F-fluoropropyl]-α-methyl tyrosine ((19)F-FPAMT)...

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Detalles Bibliográficos
Autores principales: Shih, I-Hong, Kong, Fan-Lin, Ali, Mohammad S., Zhang, Yinhan, Yu, Dong-Fang, Duan, Xudong, Yang, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722965/
https://www.ncbi.nlm.nih.gov/pubmed/23936803
http://dx.doi.org/10.1155/2013/460619