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The Synthetic Compound Norcantharidin Induced Apoptosis in Mantle Cell Lymphoma In Vivo and In Vitro through the PI3K-Akt-NF-κB Signaling Pathway

This study aimed to elucidate the antitumor activity of norcantharidin (NCTD) against human mantle cell lymphoma (MCL). Cell proliferation and apoptosis were examined by MTS and flow cytometry. Caspase-3, -8, and -9 activities were detected with a colorimetric caspase protease assay. Apoptotic prote...

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Detalles Bibliográficos
Autores principales: Lv, Hongyan, Li, Yan, Du, Hengfei, Fang, Jie, Song, Xiaoning, Zhang, Jinqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722980/
https://www.ncbi.nlm.nih.gov/pubmed/23935664
http://dx.doi.org/10.1155/2013/461487