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Expression of Tra2β in Cancer Cells as a Potential Contributory Factor to Neoplasia and Metastasis

The splicing regulator proteins SRSF1 (also known as ASF/SF2) and SRSF3 (also known as SRP20) belong to the SR family of proteins and can be upregulated in cancer. The SRSF1 gene itself is amplified in some cancer cells, and cancer-associated changes in the expression of MYC also increase SRSF1 gene...

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Detalles Bibliográficos
Autores principales: Best, Andrew, Dagliesh, Caroline, Ehrmann, Ingrid, Kheirollahi-Kouhestani, Mahsa, Tyson-Capper, Alison, Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723085/
https://www.ncbi.nlm.nih.gov/pubmed/23935626
http://dx.doi.org/10.1155/2013/843781