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Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways

BACKGROUND: Dendritic cells (DCs) are promising mediators of anti-tumor immune responses due to their potent antigen-presentation capacity. Unfortunately, cancer cells can often disarm differentiated DCs by rendering them incapable of maturation or by promoting their apoptosis. DC vaccine regimens a...

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Detalles Bibliográficos
Autores principales: Wang, James CM, Felizardo, Tânia C, Au, Bryan CY, Fowler, Daniel H, Dekaban, Gregory A, Medin, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723442/
https://www.ncbi.nlm.nih.gov/pubmed/23870437
http://dx.doi.org/10.1186/1743-422X-10-240