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Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways

BACKGROUND: Dendritic cells (DCs) are promising mediators of anti-tumor immune responses due to their potent antigen-presentation capacity. Unfortunately, cancer cells can often disarm differentiated DCs by rendering them incapable of maturation or by promoting their apoptosis. DC vaccine regimens a...

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Detalles Bibliográficos
Autores principales:	Wang, James CM, Felizardo, Tânia C, Au, Bryan CY, Fowler, Daniel H, Dekaban, Gregory A, Medin, Jeffrey A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723442/ https://www.ncbi.nlm.nih.gov/pubmed/23870437 http://dx.doi.org/10.1186/1743-422X-10-240

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