Oxidative Stress and Replication-Independent DNA Breakage Induced by Arsenic in Saccharomyces cerevisiae

Arsenic is a well-established human carcinogen of poorly understood mechanism of genotoxicity. It is generally accepted that arsenic acts indirectly by generating oxidative DNA damage that can be converted to replication-dependent DNA double-strand breaks (DSBs), as well as by interfering with DNA r...

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Detalles Bibliográficos
Autores principales: Litwin, Ireneusz, Bocer, Tomasz, Dziadkowiec, Dorota, Wysocki, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723488/
https://www.ncbi.nlm.nih.gov/pubmed/23935510
http://dx.doi.org/10.1371/journal.pgen.1003640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723488/
https://www.ncbi.nlm.nih.gov/pubmed/23935510
http://dx.doi.org/10.1371/journal.pgen.1003640

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