Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson’s patients leukocytes

BACKGROUND: Nonsense-Mediated decay (NMD) selectively degrades mRNA transcripts that carry premature stop codons. NMD is often triggered by alternative splicing (AS) modifications introducing such codons. NMD plays an important regulatory role in brain neurons, but the in vivo dynamics of AS and NMD...

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Detalles Bibliográficos
Autores principales: Soreq, Lilach, Bergman, Hagai, Israel, Zvi, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723527/
https://www.ncbi.nlm.nih.gov/pubmed/23865419
http://dx.doi.org/10.1186/1471-2164-14-478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723527/
https://www.ncbi.nlm.nih.gov/pubmed/23865419
http://dx.doi.org/10.1186/1471-2164-14-478

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