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Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson’s patients leukocytes
BACKGROUND: Nonsense-Mediated decay (NMD) selectively degrades mRNA transcripts that carry premature stop codons. NMD is often triggered by alternative splicing (AS) modifications introducing such codons. NMD plays an important regulatory role in brain neurons, but the in vivo dynamics of AS and NMD...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723527/ https://www.ncbi.nlm.nih.gov/pubmed/23865419 http://dx.doi.org/10.1186/1471-2164-14-478 |