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Recombination Dynamics of a Human Y-Chromosomal Palindrome: Rapid GC-Biased Gene Conversion, Multi-kilobase Conversion Tracts, and Rare Inversions

The male-specific region of the human Y chromosome (MSY) includes eight large inverted repeats (palindromes) in which arm-to-arm similarity exceeds 99.9%, due to gene conversion activity. Here, we studied one of these palindromes, P6, in order to illuminate the dynamics of the gene conversion proces...

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Detalles Bibliográficos
Autores principales: Hallast, Pille, Balaresque, Patricia, Bowden, Georgina R., Ballereau, Stéphane, Jobling, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723533/
https://www.ncbi.nlm.nih.gov/pubmed/23935520
http://dx.doi.org/10.1371/journal.pgen.1003666