Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)

Bacterial populations co-ordinate gene expression collectively through quorum sensing (QS), a cell-to-cell communication mechanism employing diffusible signal molecules. The LysR-type transcriptional regulator (LTTR) protein PqsR (MvfR) is a key component of alkyl-quinolone (AQ)-dependent QS in Pseu...

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Detalles Bibliográficos
Autores principales: Ilangovan, Aravindan, Fletcher, Matthew, Rampioni, Giordano, Pustelny, Christian, Rumbaugh, Kendra, Heeb, Stephan, Cámara, Miguel, Truman, Alex, Chhabra, Siri Ram, Emsley, Jonas, Williams, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723537/
https://www.ncbi.nlm.nih.gov/pubmed/23935486
http://dx.doi.org/10.1371/journal.ppat.1003508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723537/
https://www.ncbi.nlm.nih.gov/pubmed/23935486
http://dx.doi.org/10.1371/journal.ppat.1003508

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