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Block of mouse Slo1 and Slo3 K(+) channels by CTX, IbTX, TEA, 4-AP and quinidine

pH-regulated Slo3 channels, perhaps exclusively expressed in mammalian sperm, may play a role in alkalization-mediated K(+) fluxes associated with sperm capacitation. The Slo3 channel shares extensive homology with Ca(2+)- and voltage-regulated BK-type Slo1 K(+) channels. Here, using heterologous ex...

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Detalles Bibliográficos
Autores principales: Tang, Qiong-Yao, Zhang, Zhe, Xia, Xiao-Ming, Lingle, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723589/
https://www.ncbi.nlm.nih.gov/pubmed/19934650
http://dx.doi.org/10.4161/chan.4.1.10481