P2X(4) Assembles with P2X(7) and Pannexin-1 in Gingival Epithelial Cells and Modulates ATP-induced Reactive Oxygen Species Production and Inflammasome Activation

We have previously reported that Porphyromonas gingivalis infection of gingival epithelial cells (GEC) requires an exogenous danger signal such as ATP to activate an inflammasome and caspase-1, thereby inducing secretion of interleukin (IL)-1β. Stimulation with extracellular ATP also stimulates prod...

Descripción completa

Detalles Bibliográficos
Autores principales: Hung, Shu-Chen, Choi, Chul Hee, Said-Sadier, Najwane, Johnson, Larry, Atanasova, Kalina Rosenova, Sellami, Hanen, Yilmaz, Özlem, Ojcius, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723664/
https://www.ncbi.nlm.nih.gov/pubmed/23936165
http://dx.doi.org/10.1371/journal.pone.0070210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723664/
https://www.ncbi.nlm.nih.gov/pubmed/23936165
http://dx.doi.org/10.1371/journal.pone.0070210

Ejemplares similares