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P2X(4) Assembles with P2X(7) and Pannexin-1 in Gingival Epithelial Cells and Modulates ATP-induced Reactive Oxygen Species Production and Inflammasome Activation
We have previously reported that Porphyromonas gingivalis infection of gingival epithelial cells (GEC) requires an exogenous danger signal such as ATP to activate an inflammasome and caspase-1, thereby inducing secretion of interleukin (IL)-1β. Stimulation with extracellular ATP also stimulates prod...
Autores principales: | Hung, Shu-Chen, Choi, Chul Hee, Said-Sadier, Najwane, Johnson, Larry, Atanasova, Kalina Rosenova, Sellami, Hanen, Yilmaz, Özlem, Ojcius, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723664/ https://www.ncbi.nlm.nih.gov/pubmed/23936165 http://dx.doi.org/10.1371/journal.pone.0070210 |
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