Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice

How pathogenic bacteria adapt and evolve in the complex and variable environment of the host remains a largely unresolved question. Here we have used whole genome sequencing of Salmonella enterica serovar Typhimurium LT2 populations serially passaged in mice to identify mutations that adapt bacteria...

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Detalles Bibliográficos
Autores principales: Koskiniemi, Sanna, Gibbons, Henry S., Sandegren, Linus, Anwar, Naeem, Ouellette, Gary, Broomall, Stacey, Karavis, Mark, McGregor, Paul, Liem, Alvin, Fochler, Ed, McNew, Lauren, Rosenzweig, Carolyn Nicole, Rhen, Mikael, Skowronski, Evan W., Andersson, Dan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723669/
https://www.ncbi.nlm.nih.gov/pubmed/23936152
http://dx.doi.org/10.1371/journal.pone.0070147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723669/
https://www.ncbi.nlm.nih.gov/pubmed/23936152
http://dx.doi.org/10.1371/journal.pone.0070147

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