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Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice
How pathogenic bacteria adapt and evolve in the complex and variable environment of the host remains a largely unresolved question. Here we have used whole genome sequencing of Salmonella enterica serovar Typhimurium LT2 populations serially passaged in mice to identify mutations that adapt bacteria...
Autores principales: | Koskiniemi, Sanna, Gibbons, Henry S., Sandegren, Linus, Anwar, Naeem, Ouellette, Gary, Broomall, Stacey, Karavis, Mark, McGregor, Paul, Liem, Alvin, Fochler, Ed, McNew, Lauren, Rosenzweig, Carolyn Nicole, Rhen, Mikael, Skowronski, Evan W., Andersson, Dan I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723669/ https://www.ncbi.nlm.nih.gov/pubmed/23936152 http://dx.doi.org/10.1371/journal.pone.0070147 |
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