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Aberrant Expression of Beclin-1 and LC3 Correlates with Poor Prognosis of Human Hypopharyngeal Squamous Cell Carcinoma

BACKGROUND: Beclin-1, a key regulator of autophagy. Microtubule-associated protein 1 light chain 3 (LC3), is involved in autophagsome formation during autophagy. The autophagic genes beclin-1 and LC3 paly an important role in the development and progression of tumor. This study was designed to inves...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Pan, Xin-Liang, Ding, Li-Jie, Liu, Da-Yu, Da-Peng Lei, Jin, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723780/
https://www.ncbi.nlm.nih.gov/pubmed/23935917
http://dx.doi.org/10.1371/journal.pone.0069038