Preconditioning with Associated Blocking of Ca(2+) Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells

OBJECTIVE: Beta cells of pancreatic islets are susceptible to functional deficits and damage by hypoxia. Here we aimed to characterize such effects and to test for and pharmacological means to alleviate a negative impact of hypoxia. METHODS AND DESIGN: Rat and human pancreatic islets were subjected...

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Detalles Bibliográficos
Autores principales: Ma, Zuheng, Moruzzi, Noah, Catrina, Sergiu-Bogdan, Hals, Ingrid, Oberholzer, José, Grill, Valdemar, Björklund, Anneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723782/
https://www.ncbi.nlm.nih.gov/pubmed/23935835
http://dx.doi.org/10.1371/journal.pone.0067498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723782/
https://www.ncbi.nlm.nih.gov/pubmed/23935835
http://dx.doi.org/10.1371/journal.pone.0067498

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