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Pharmacological Induction of Transforming Growth Factor-Beta1 in Rat Models Enhances Radiation Injury in the Intestine and the Heart

Radiation therapy in the treatment of cancer is dose limited by radiation injury in normal tissues such as the intestine and the heart. To identify the mechanistic involvement of transforming growth factor-beta 1 (TGF-β1) in intestinal and cardiac radiation injury, we studied the influence of pharma...

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Detalles Bibliográficos
Autores principales: Boerma, Marjan, Wang, Junru, Sridharan, Vijayalakshmi, Herbert, Jean-Marc, Hauer-Jensen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723823/
https://www.ncbi.nlm.nih.gov/pubmed/23936211
http://dx.doi.org/10.1371/journal.pone.0070479