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Pharmacological Induction of Transforming Growth Factor-Beta1 in Rat Models Enhances Radiation Injury in the Intestine and the Heart
Radiation therapy in the treatment of cancer is dose limited by radiation injury in normal tissues such as the intestine and the heart. To identify the mechanistic involvement of transforming growth factor-beta 1 (TGF-β1) in intestinal and cardiac radiation injury, we studied the influence of pharma...
Autores principales: | Boerma, Marjan, Wang, Junru, Sridharan, Vijayalakshmi, Herbert, Jean-Marc, Hauer-Jensen, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723823/ https://www.ncbi.nlm.nih.gov/pubmed/23936211 http://dx.doi.org/10.1371/journal.pone.0070479 |
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