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Prenatal Exposure to Dexamethasone in the Mouse Alters Cardiac Growth Patterns and Increases Pulse Pressure in Aged Male Offspring

Exposure to synthetic glucocorticoids during development can result in later cardiovascular and renal disease in sheep and rats. Although prenatal glucocorticoid exposure is associated with impaired renal development, less is known about effects on the developing heart. This study aimed to examine t...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Lee, Cuffe, James S. M., Paravicini, Tamara M., Campbell, Sally, Dickinson, Hayley, Singh, Reetu R., Gezmish, Oksan, Black, M. Jane, Moritz, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723833/
https://www.ncbi.nlm.nih.gov/pubmed/23935943
http://dx.doi.org/10.1371/journal.pone.0069149