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A Prospective Study of Bone Marrow Hematopoietic and Mesenchymal Stem Cells in Type 1 Gaucher Disease Patients

Gaucher disease (GD) is an autosomal recessive disorder characterized by lysosomal glucocerebrosidase (GBA) deficiency leading to hematological and skeletal manifestations. Mechanisms underlying these symptoms have not yet been elucidated. In vivo, bone marrow (BM) mesenchymal stem cells (MSCs) have...

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Detalles Bibliográficos
Autores principales: Lecourt, Séverine, Mouly, Enguerran, Freida, Delphine, Cras, Audrey, Ceccaldi, Raphaël, Heraoui, Djazia, Chomienne, Christine, Marolleau, Jean-Pierre, Arnulf, Bertrand, Porcher, Raphael, Caillaud, Catherine, Vanneaux, Valérie, Belmatoug, Nadia, Larghero, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723887/
https://www.ncbi.nlm.nih.gov/pubmed/23935976
http://dx.doi.org/10.1371/journal.pone.0069293