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Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores

BACKGROUND: Two main shortcomings of classical allergen-specific immunotherapy are long treatment duration and low patient compliance. Utilizing the unique immunological features of the skin by transcutaneous application of antigen opens new approaches not only for painless vaccine delivery, but als...

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Detalles Bibliográficos
Autores principales: Hessenberger, Michael, Weiss, Richard, Weinberger, Esther E., Boehler, Christof, Thalhamer, Josef, Scheiblhofer, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724055/
https://www.ncbi.nlm.nih.gov/pubmed/23273971
http://dx.doi.org/10.1016/j.vaccine.2012.09.086