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Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores
BACKGROUND: Two main shortcomings of classical allergen-specific immunotherapy are long treatment duration and low patient compliance. Utilizing the unique immunological features of the skin by transcutaneous application of antigen opens new approaches not only for painless vaccine delivery, but als...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724055/ https://www.ncbi.nlm.nih.gov/pubmed/23273971 http://dx.doi.org/10.1016/j.vaccine.2012.09.086 |