The splicing regulator PTBP2 is an AID interacting protein and promotes binding of AID to switch region DNA

During immunoglobulin class switch recombination (CSR), activation induced cytidine deaminase (AID) induces DNA double strand breaks into transcribed, repetitive DNA elements called switch sequences. The mechanism that promotes the binding of AID specifically to switch regions remains to be elucidat...

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Detalles Bibliográficos
Autores principales: Nowak, Urszula, Matthews, Allysia, Zheng, Simin, Chaudhuri, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724472/
https://www.ncbi.nlm.nih.gov/pubmed/21186367
http://dx.doi.org/10.1038/ni.1977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724472/
https://www.ncbi.nlm.nih.gov/pubmed/21186367
http://dx.doi.org/10.1038/ni.1977

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