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Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer’s disease

BACKGROUND: The aggregates of a protein called, ‘Aβ’ found in brains of Alzheimer’s patients are strongly believed to be the cause for neuronal death and cognitive decline. Among the different forms of Aβ aggregates, smaller aggregates called ‘soluble oligomers’ are increasingly believed to be the p...

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Detalles Bibliográficos
Autores principales: Ghosh, Preetam, Kumar, Amit, Datta, Bhaswati, Rangachari, Vijayaraghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724481/
https://www.ncbi.nlm.nih.gov/pubmed/20946608
http://dx.doi.org/10.1186/1471-2105-11-S6-S24