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Transcriptional analysis of the effect of exogenous decanoic acid stress on Streptomyces roseosporus
BACKGROUD: Daptomycin is an important antibiotic against infections caused by drug-resistant pathogens. Its production critically depends on the addition of decanoic acid during fermentation. Unfortunately, decanoic acid (>2.5 mM) is toxic to daptomycin producer, Streptomyces roseosporus. RESULTS...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724488/ https://www.ncbi.nlm.nih.gov/pubmed/23432849 http://dx.doi.org/10.1186/1475-2859-12-19 |