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Transcriptional analysis of the effect of exogenous decanoic acid stress on Streptomyces roseosporus

BACKGROUD: Daptomycin is an important antibiotic against infections caused by drug-resistant pathogens. Its production critically depends on the addition of decanoic acid during fermentation. Unfortunately, decanoic acid (>2.5 mM) is toxic to daptomycin producer, Streptomyces roseosporus. RESULTS...

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Detalles Bibliográficos
Autores principales: Liao, Guojian, Liu, Qing, Xie, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724488/
https://www.ncbi.nlm.nih.gov/pubmed/23432849
http://dx.doi.org/10.1186/1475-2859-12-19