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Extracellular DNA-induced antimicrobial peptide resistance in Salmonella enterica serovar Typhimurium

BACKGROUND: The Salmonella enterica serovar Typhimurium PhoPQ two component system (TCS) is activated by low Mg(2+) levels, low pH and by antimicrobial peptides (AP). Under Mg(2+) limitation, the PhoPQ system induces pmrD expression, which post-translationally activates the PmrAB TCS. PhoPQ and PmrA...

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Detalles Bibliográficos
Autores principales: Johnson, Lori, Horsman, Shawn R, Charron-Mazenod, Laetitia, Turnbull, Amy L, Mulcahy, Heidi, Surette, Michael G, Lewenza, Shawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724500/
https://www.ncbi.nlm.nih.gov/pubmed/23705831
http://dx.doi.org/10.1186/1471-2180-13-115